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Glomerular Disorders

Hematuria, Proteinuria, and Glomerulonephritis

Pediatric Nephrology Review
Frank Tenney MD

Overview:

Hematuria
Proteinuria
Nephritic Syndrome
Nephrotic Syndrome

CPC:

Hematuria
Proteinuria
Glomerulonephritis, Acute

References:

Hematuria - a practical primary care approach

Proteinuria - a practical approach

Proteinuria and nephrotic syndrome - evaluation and management

Manifestations of nephrotic and nephritic features - table

From Brenner & Rector's The Kidney, 7th ed., Copyright © 2004

Proteinuria

Nephrotic Syndrome

Recurrent or persistent hematuria

Algorithms:

Pathophysiology of NS

Lipoproteins in NS

Evaluation of proteinuria in children

Evaluation of asymptomatic microhematuria in children

Evaluation of hematuria and proteinuria in children

Evaluation of gross hematuria in children

Mechanisms of glomerular damage

Images

EM glomerulus

LM glomerulus

SEM glomerulus

PIAGN proliferation

PIAGN IC deposits

PIAGN IF

PIAGN crescents